Ziwig Endotest® | CareBridge Medical
Private endometriosis assessment at CareBridge Medical

A new route to clearer answers

Ziwig Endotest®

A prescription-only, non-invasive saliva test designed to support the diagnosis of endometriosis in symptomatic patients aged 18–43.

Non-invasive saliva sample Clinician-led assessment For symptomatic patients aged 18–43

Clinical assessment is required. Suitability is confirmed by your CareBridge clinician.

What is Ziwig Endotest?

A simple saliva sample. Advanced molecular analysis.

Ziwig Endotest® is an in-vitro diagnostic medical device used on medical prescription. It analyses a pattern of salivary microRNAs using next-generation sequencing and artificial intelligence.

The test is intended to help confirm or rule out endometriosis with a high degree of reliability, particularly when symptoms suggest endometriosis and imaging is normal, unclear or has not provided a complete explanation.

It does not replace a clinical consultation, pelvic imaging or specialist review where these are required. Your clinician will interpret the result in the context of your symptoms and medical history.

>97%reported sensitivity
>93%reported specificity
18–43validated age range

Why patients consider testing

Designed to bring clarity to complex symptoms.

01

Non-invasive collection

The laboratory analysis begins with a saliva sample collected using the supplied medical collection kit.

02

May help when imaging is uncertain

The test can be particularly useful where symptoms remain suggestive but ultrasound or other imaging has been normal or inconclusive.

03

Clinical interpretation included

Your result is reviewed alongside your symptoms, history and any relevant examination or imaging findings.

Symptoms and suitability

Could endometriosis be contributing to your symptoms?

Endometriosis symptoms vary widely and can overlap with other conditions. The presence of symptoms does not confirm endometriosis, but it may warrant clinical assessment.

Severe period painPain that disrupts work, study, sleep or normal activities.
Chronic pelvic painPersistent or recurring pain in the lower abdomen, pelvis or back.
Pain during or after sexDeep pelvic discomfort associated with intercourse.
Painful bowel movementsParticularly cyclical pain or rectal bleeding around menstruation.
Painful urinationCyclical urinary pain or blood in the urine during menstruation.
Difficulty conceivingInfertility alongside one or more symptoms suggestive of endometriosis.
Fatigue and digestive symptomsFatigue, bloating, diarrhoea or constipation may occur alongside pain.
Shoulder-tip painUnusual cyclical pain should be discussed with a clinician.

Who may be suitable

  • Patients aged 18–43 with one or more symptoms suggestive of endometriosis.
  • Patients taking hormonal treatment; the test can still be performed.
  • Testing can be performed at any point in the menstrual cycle.
  • Patients whose symptoms require further assessment after normal or equivocal imaging.

When testing may not be suitable

  • Current pregnancy.
  • A medical history of cancer or HIV.
  • An active infection at the time of saliva collection.
  • Contamination of the sample by blood, nasal secretions, food, toothpaste, lipstick, tobacco or chewing gum.
  • Any other contraindication identified during your medical consultation.

Your appointment journey

From consultation to a clinically reviewed result.

Your exact pathway depends on the appointment type selected and your individual clinical needs.

Clinical consultation

A clinician reviews your symptoms, history, suitability and any previous investigations.

Sample collection

You provide the saliva sample in accordance with the collection instructions.

Laboratory analysis

Salivary microRNA is analysed using sequencing and an algorithm developed for the test.

Result and next steps

Your clinician explains the result and advises on appropriate follow-up, imaging or specialist care.

Preparing for your saliva sample

Small steps that protect sample quality.

For at least 30 minutes before collection, follow the instructions supplied by the clinic and collection kit.

Do not eat or drinkAvoid food and beverages during the preparation period.
Do not smoke or chew gumTobacco and chewing gum can contaminate the sample.
Do not brush your teethToothpaste residue or gum bleeding may affect sample quality.
Do not wear lipstickLip products must not enter the collection tube.
Wash your handsUse clean hands when opening and handling the collection components.
Tell the clinic if you are unwellTesting should not be performed during an active infection.

Choose your clinical pathway

Two appointment options, tailored to the level of review you need.

Both pathways include medical assessment and Ziwig Endotest® testing. Availability and clinical suitability are confirmed at appointment.

Focused testing pathway

Endotest + General Physician Consultation

€1,350 total appointment price

  • Consultation with a General Physician
  • Clinical history and suitability review
  • Ziwig Endotest® saliva collection
  • Laboratory testing
  • Clinical review of your result and recommended next steps
Book this appointment

Frequently asked questions

Helpful information before booking.

Is Ziwig Endotest® a replacement for ultrasound or laparoscopy?

No. It is an additional diagnostic tool. Ultrasound remains important for evaluating pelvic anatomy and identifying some forms of endometriosis or other causes of symptoms. Further investigation may still be advised based on your clinical findings.

Can I take the test while using hormonal contraception or treatment?

According to the manufacturer, the test may be performed while using hormonal treatment. Your clinician will confirm suitability during your consultation.

Does the test have to be performed on a particular day of my cycle?

No. Manufacturer information states that it can be performed at any time during the menstrual cycle.

What happens if my result is positive?

Your clinician will discuss what the result means in the context of your symptoms and recommend the appropriate next steps. These may include treatment, imaging, specialist review or further investigation.

What happens if my result is negative?

A negative result is interpreted together with your medical history and clinical findings. Persistent or concerning symptoms may still require assessment for other gynaecological, gastrointestinal, urinary or musculoskeletal causes.

How quickly will I receive my result?

Laboratory turnaround can vary. The clinic will advise you of the expected timeframe and how your result will be communicated.

Take the next step

Choose the assessment pathway that feels right for you.

A CareBridge clinician will review your suitability, explain the process and help you understand the result in the context of your health.

Trademark and provider disclaimer: CareBridge Medical does not own, manufacture or hold proprietary rights in Ziwig Endotest®. Ziwig Endotest® and its associated trademarks, technology and intellectual property belong to their respective owners. CareBridge Medical acts solely as an independent healthcare service provider, arranging access to the test and providing medical consultation, clinical assessment, sample collection, result review and related medical care through qualified practitioners.